Submission Details

MAT-POS-fce787c2
Molecule(s):
CCOc1c(Cl)cccc1CC(=O)Nc1cncc2ccccc12

MAT-POS-fce787c2-1

CCOc1c(Cl)cccc1CC(=O)Nc1cncc2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cc(Cl)cc(Cl)c1)Nc1cncc2ccccc12

MAT-POS-fce787c2-2

O=C(Cc1cc(Cl)cc(Cl)c1)Nc1cncc2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
CC(C(=O)Nc1cncc2ccccc12)c1ccc(Cl)c(Cl)c1

MAT-POS-fce787c2-3

CC(C(=O)Nc1cncc2ccccc12)c1ccc(Cl)c(Cl)c1

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C(O)c1ccc(Cl)c(Cl)c1

MAT-POS-fce787c2-4

O=C(Nc1cncc2ccccc12)C(O)c1ccc(Cl)c(Cl)c1

3-aminopyridine-like Assayed Check Availability on Manifold View
CNC(C(=O)Nc1cncc2ccccc12)c1ccc(Cl)c(Cl)c1

MAT-POS-fce787c2-5

CNC(C(=O)Nc1cncc2ccccc12)c1ccc(Cl)c(Cl)c1

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C(F)(F)c1ccc(Cl)c(Cl)c1

MAT-POS-fce787c2-6

O=C(Nc1cncc2ccccc12)C(F)(F)c1ccc(Cl)c(Cl)c1

3-aminopyridine-like Assayed Check Availability on Manifold View
CC(N)(C(=O)Nc1cncc2ccccc12)c1ccc(Cl)c(Cl)c1

MAT-POS-fce787c2-7

CC(N)(C(=O)Nc1cncc2ccccc12)c1ccc(Cl)c(Cl)c1

3-aminopyridine-like Ordered Check Availability on Manifold View
N#CC(C(=O)Nc1cncc2ccccc12)c1ccc(Cl)c(Cl)c1

MAT-POS-fce787c2-8

N#CC(C(=O)Nc1cncc2ccccc12)c1ccc(Cl)c(Cl)c1

3-aminopyridine-like Assayed Check Availability on Manifold View
CNC(C)(C(=O)Nc1cncc2ccccc12)c1ccc(Cl)c(Cl)c1

MAT-POS-fce787c2-9

CNC(C)(C(=O)Nc1cncc2ccccc12)c1ccc(Cl)c(Cl)c1

3-aminopyridine-like Ordered Check Availability on Manifold View
CN(C)CCNC(C(=O)Nc1cncc2ccccc12)c1ccc(Cl)c(Cl)c1

MAT-POS-fce787c2-10

CN(C)CCNC(C(=O)Nc1cncc2ccccc12)c1ccc(Cl)c(Cl)c1

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C(CO)c1ccc(Cl)c(Cl)c1

MAT-POS-fce787c2-11

O=C(Nc1cncc2ccccc12)C(CO)c1ccc(Cl)c(Cl)c1

3-aminopyridine-like Assayed Check Availability on Manifold View
Design Rationale:

Building on RAL-THA-2d450e86, doing quick parallel Chemistry exploring P2 site

Discussion:

Contributor: Matt Robinson, PostEra - Wed, 23 Dec 2020 07:30:07 +0000