Submission Details

EDJ-MED-fb4b7746
Molecule(s):
Cn1cnc2cncc(NC(=O)[C@@H]3CCOc4ccc(Cl)cc43)c21

EDJ-MED-fb4b7746-1

Cn1cnc2cncc(NC(=O)[C@@H]3CCOc4ccc(Cl)cc43)c21

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Nc1cncc2nc[nH]c12)[C@@H]1CCOc2ccc(Cl)cc21

EDJ-MED-fb4b7746-2

O=C(Nc1cncc2nc[nH]c12)[C@@H]1CCOc2ccc(Cl)cc21

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Nc1cncc2[nH]c(=O)[nH]c12)[C@@H]1CCOc2ccc(Cl)cc21

EDJ-MED-fb4b7746-3

O=C(Nc1cncc2[nH]c(=O)[nH]c12)[C@@H]1CCOc2ccc(Cl)cc21

3-aminopyridine-like Ordered Check Availability on Manifold View
Cn1c(=O)[nH]c2cncc(NC(=O)[C@@H]3CCOc4ccc(Cl)cc43)c21

EDJ-MED-fb4b7746-4

Cn1c(=O)[nH]c2cncc(NC(=O)[C@@H]3CCOc4ccc(Cl)cc43)c21

3-aminopyridine-like Ordered Check Availability on Manifold View
Design Rationale:

Learning from MAT-POS-f7918075-8 aiming to reduce logP and metabolism on isoquinoline.

Discussion:

Contributor: Ed J Griffen, MedChemica Ltd - Thu, 05 Nov 2020 20:17:47 +0000