Submission Details

Molecule(s):
COc1cccc(C2=N/C(=C/c3sccc3C)C(=O)O2)c1

MAT-POS-fa06b69f-1
Duplicate of:
MAT-POS-ea426761-9

COc1cccc(C2=N/C(=C/c3sccc3C)C(=O)O2)c1

CSC1=C(C#N)C2(CCCCC2)C(C#N)=C(NC(=O)CCl)N1

MAT-POS-fa06b69f-2
Duplicate of:
TAT-ENA-80bfd3e5-7

CSC1=C(C#N)C2(CCCCC2)C(C#N)=C(NC(=O)CCl)N1

Cc1c(C(=O)CCl)c2ccccn2c1C(=O)c1ccc(F)cc1

MAT-POS-fa06b69f-3
Duplicate of:
TAT-ENA-80bfd3e5-4

Cc1c(C(=O)CCl)c2ccccn2c1C(=O)c1ccc(F)cc1

Cc1cc(C(=O)CCl)c(C)n1CC1COc2ccccc2O1

MAT-POS-fa06b69f-4
Duplicate of:
TAT-ENA-80bfd3e5-32

Cc1cc(C(=O)CCl)c(C)n1CC1COc2ccccc2O1

CCN(c1ccccc1)S(=O)(=O)c1ccc(OC)c(NC(=O)CCl)c1

MAT-POS-fa06b69f-5
Duplicate of:
TAT-ENA-80bfd3e5-36

CCN(c1ccccc1)S(=O)(=O)c1ccc(OC)c(NC(=O)CCl)c1

O=C1OC(c2cccs2)=N/C1=C\c1ccc(N2CCOCC2)s1

MAT-POS-fa06b69f-6

O=C1OC(c2cccs2)=N/C1=C\c1ccc(N2CCOCC2)s1

CS(=O)(=O)Nc1cccc(C2=NN(C(=O)CCl)C(c3ccccc3)C2)c1

MAT-POS-fa06b69f-7
Duplicate of:
TAT-ENA-80bfd3e5-45

CS(=O)(=O)Nc1cccc(C2=NN(C(=O)CCl)C(c3ccccc3)C2)c1

CN(CC(=O)Nc1ccccc1Br)C(=O)CCl

MAT-POS-fa06b69f-8
Duplicate of:
TAT-ENA-80bfd3e5-42

CN(CC(=O)Nc1ccccc1Br)C(=O)CCl

Duplicate Ugi Assayed Check Availability on Manifold View
Cc1cc(C(=O)CCl)c(C)n1NC(=O)c1n[nH]c(=O)c2ccccc12

MAT-POS-fa06b69f-9
Duplicate of:
TAT-ENA-80bfd3e5-37

Cc1cc(C(=O)CCl)c(C)n1NC(=O)c1n[nH]c(=O)c2ccccc12


Design Rationale:

Follow up on HTS hits that are available from Enamine

Discussion: