Submission Details

MAT-POS-f7918075
Molecule(s):
O=C(Nc1cncc2ccccc12)C1CCOc2ccc(Cl)cc21

MAT-POS-f7918075-1
Duplicate of:
VLA-UCB-1dbca3b4-15

O=C(Nc1cncc2ccccc12)C1CCOc2ccc(Cl)cc21

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1COc2ccc(Cl)cc21

MAT-POS-f7918075-2

O=C(Nc1cncc2ccccc12)C1COc2ccc(Cl)cc21

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2ncccc12

MAT-POS-f7918075-3
Duplicate of:
MIC-UNK-08cd9c58-1

O=C(Cc1cccc(Cl)c1)Nc1cncc2ncccc12

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2[nH]c(=O)[nH]c12

MAT-POS-f7918075-4
Duplicate of:
MIC-UNK-8971c93c-1

O=C(Cc1cccc(Cl)c1)Nc1cncc2[nH]c(=O)[nH]c12

Duplicate 3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2ccncc12

MAT-POS-f7918075-5

O=C(Cc1cccc(Cl)c1)Nc1cncc2ccncc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cnnc2ccccc12

MAT-POS-f7918075-6
Duplicate of:
EDJ-MED-50fe53e8-2

O=C(Cc1cccc(Cl)c1)Nc1cnnc2ccccc12

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2c1CC(=O)N2

MAT-POS-f7918075-7

O=C(Cc1cccc(Cl)c1)Nc1cncc2c1CC(=O)N2

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cncc2nc[nH]c12

MAT-POS-f7918075-8

O=C(Cc1cccc(Cl)c1)Nc1cncc2nc[nH]c12

3-aminopyridine-like Assayed Check Availability on Manifold View
Design Rationale:

All quick follow ups to isoquinoline hit. First two are via amide coupling while rest are from buchwald route with Br https://www.enaminestore.com/realdb/Z1675865540, https://www.enaminestore.com/realdb/Z1848696683, EN300-238641, EN300-6778201, EN300-6786798, EN300-300425, EN300-300425, EN300-84249

Discussion:

Contributor: Matt Robinson, PostEra - Tue, 18 Aug 2020 05:00:53 +0000