Submission Details

MAT-POS-ee5e8e94
Molecule(s):
CN(C)Cc1cc2c(NC(=O)C3CCOc4ccc(Cl)cc43)cncc2s1

MAT-POS-ee5e8e94-1

CN(C)Cc1cc2c(NC(=O)C3CCOc4ccc(Cl)cc43)cncc2s1

3-aminopyridine-like Ordered Check Availability on Manifold View
CN(C)C(=O)c1cc2c(NC(=O)C3CCOc4ccc(Cl)cc43)cncc2s1

MAT-POS-ee5e8e94-2

CN(C)C(=O)c1cc2c(NC(=O)C3CCOc4ccc(Cl)cc43)cncc2s1

3-aminopyridine-like Assayed Check Availability on Manifold View
Design Rationale:

going from primary and secondary amide to tertiary to try to improve potency.

Discussion:

Contributor: Matt Robinson, PostEra - Mon, 28 Jun 2021 04:22:24 +0000