Submission Details
Molecule(s):
COc1cc2c([C@@H](C)CNC(C)=O)c[nH]c2cc1Cl
CCC(=O)NCC[C@@H]1CCc2ccc3c(c21)CCO3
COc1ccc2cccc(CCNC(C)=O)c2c1
CCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1CCO2
Design Rationale:
Clinical-phase melatonin receptor agonist similar to Diamond hit x0104
Other Notes:
Suggested by Alpha Lee following observation by Martin Smiesko and Markus Lill that Diamond hit x0104 was remarkably similar to melatonin (with -F instead of -OMe substituent on indole ring)