Submission Details
Molecule(s):
COc1ccc(Cl)cc1OCCNC(=O)C1C(=O)Nc2ccccc21
COc1ccc(Cl)cc1OCCNC(=O)C1(C)C(=O)Nc2cccc(OC)c21
COc1cc(Cl)c(Cl)cc1OCCNC(=O)c1cc(=O)[nH]c2cccc(OC)c12
COc1cc(Cl)c(Cl)cc1OCCNC(=O)C1C(=O)Nc2cccc(OC)c21
COc1cc(Cl)c(Cl)cc1OCCNC(=O)C1(C)C(=O)Nc2cccc(OC)c21
Design Rationale:
Revisiting quinolinone series with dichloro and a replacement attempt to indolone.