O=C1C=CC(=O)N1N(C(=O)C1CCOc2ccc(Cl)cc21)c1cncc2ccccc12
O=C(Nc1cccc2ccnc(N3C(=O)C=CC3=O)c12)C1CCOc2ccc(Cl)cc21
O=C(C1CCOc2ccc(Cl)cc21)C(c1cncc2ccccc12)N1C(=O)C=CC1=O
O=C1C=CC(=O)N1C(F)(C(=O)C1CCOc2ccc(Cl)cc21)c1cncc2ccccc12
C=CS(=O)(=O)NN(C(=O)C1(F)CCOc2ccc(Cl)cc21)c1cncc2ccccc12
C=CS(=O)(=O)NN(C(=O)C1CCOc2ccc(Cl)cc21)c1cncc2ccccc12
O=C(C1CCOc2ccc(Cl)cc21)N(NS(=O)(=O)F)c1cncc2ccccc12
C=CS(=O)(=O)Nc1nccc2cccc(NC(=O)C3CCOc4ccc(Cl)cc43)c12
Another idea of a Cys warhead. Chemical (experimental( strategies are proving difficult. This might be sufficiently stable and readily synthesised,
Racemate exemplar shown. Might be applicable to other leads as well as (R)- and (S)- forms in potent ones. F might add some configurational stability and prevent racemization.