NS(=O)(=O)c1cccc(C2(CC(=O)Nc3cccnc3)CCCCC2)c1
NS(=O)(=O)c1cccc(C2(CC(=O)Nc3cccnc3)CCCC2)c1
NS(=O)(=O)c1cccc(C2(CC(=O)Nc3cccnc3)CCC2)c1
Cc1ccncc1NC(=O)CC1(c2cccc(S(N)(=O)=O)c2)CCCCC1
Cc1ccncc1NC(=O)CC1(c2cccc(S(N)(=O)=O)c2)CCCC1
Cc1ccncc1NC(=O)CC1(c2cccc(S(N)(=O)=O)c2)CCC1
Structure-Based Design: - Combination of X_0678 and X_0946 - Combination of cyclopentyl version of X_0678 and X_0946 - Combination of cyclobutyl version of X_0678 and X_0946 - Combination of X_0678 and X_0946 with methyl substitution to lock pyridine conformation - Combination of cyclopentyl version of X_0678 and X_0946 with methyl substitution to lock pyridine conformation - Combination of cyclobutyl version of X_0678 and X_0946 with methyl substitution to lock pyridine conformation