Submission Details
Molecule(s):
O=c1[nH]cc(-c2cccc(Cl)c2)c(=O)n1-c1cncc2ccccc12
O=c1[nH]cc(-c2ccccc2)c(=O)n1-c1cncc2ccccc12
Design Rationale:
Transform two sp3 carbons of PET-UNK-abc197b8-1 to sp2 carbon. These two designs are likely to be less potent than starting point but may be more synthetically and they also lack the chiral center. The amide NH can be used as a vector for further elaboration.