CSC1(C(=O)Nc2cncc3ccccc23)CNC(=O)c2ccc(Cl)cc21
JOH-UNI-e398da21-2
Duplicate of:
MIC-UNK-6e9f8a43-1
CSC1(C(=O)Nc2cncc3ccccc23)CN(S(C)(=O)=O)Cc2ccc(Cl)cc21
Would a S enable a sigma hole interatcion and comformationally lock this?
SMe vs OMe bioisoster examples.