Submission Details

ALE-ALC-e1a61ec1

Molecule(s):

N#CC1(CS(=O)(=O)N2Cc3ccc(Cl)cc3[C@H](C(=O)Nc3cncc4c(C=O)cccc34)C2)CC1

ALE-ALC-e1a61ec1-1

N#CC1(CS(=O)(=O)N2Cc3ccc(Cl)cc3[C@H](C(=O)Nc3cncc4c(C=O)cccc34)C2)CC1

Check Availability on Manifold View

Design Rationale:

the presence of a nitrogen near where the carboxyl group is when in side protease

Inspired By:

N#CC1(CS(=O)(=O)N2Cc3ccc(Cl)cc3[C@@H](C(=O)Nc3cncc4c(C(=O)O)cccc34)C2)CC1

ALE-ALC-1b189c66-1

N#CC1(CS(=O)(=O)N2Cc3ccc(Cl)cc3C3(CCN(c4cncc5ccc(OCCO)cc45)C3=O)C2)CC1

MAT-POS-1a788f51-1

Discussion:

Contributor: alex, alchemical biological research - Sun, 01 Jan 2023 11:25:45 +0000