Submission Details

MAT-POS-e119ab4f
Molecule(s):
CNC(=O)CN1CC(C(=O)Nc2cncc3cc(F)ccc23)c2cc(Cl)ccc2C1=O

MAT-POS-e119ab4f-1

CNC(=O)CN1CC(C(=O)Nc2cncc3cc(F)ccc23)c2cc(Cl)ccc2C1=O

CNC(=O)CN1CC(C(=O)Nc2cncc3ccc(F)cc23)c2cc(Cl)ccc2C1=O

MAT-POS-e119ab4f-2

CNC(=O)CN1CC(C(=O)Nc2cncc3ccc(F)cc23)c2cc(Cl)ccc2C1=O

CNC(=O)CN1CC(C(=O)Nc2cncc3cccc(C)c23)c2cc(Cl)ccc2C1=O

MAT-POS-e119ab4f-3

CNC(=O)CN1CC(C(=O)Nc2cncc3cccc(C)c23)c2cc(Cl)ccc2C1=O

O=C(Nc1cncc2ccccc12)C12CC(C1)Oc1ccc(Cl)cc12

MAT-POS-e119ab4f-4

O=C(Nc1cncc2ccccc12)C12CC(C1)Oc1ccc(Cl)cc12

CNC(=O)CN1CC(C)(C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2S1(=O)=O

MAT-POS-e119ab4f-5

CNC(=O)CN1CC(C)(C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2S1(=O)=O

3-aminopyridine-like Assayed Check Availability on Manifold View
Design Rationale:

New targets with very focused designs attempting to probe biochemical and antiviral potency of these combinations of P1 and P2

Discussion:

Contributor: Matt Robinson, PostEra - Mon, 06 Sep 2021 06:15:59 +0000