Submission Details

Molecule(s):
OCCn1c(CSc2nc3ccccc3o2)nc2ccc(Cl)cc21

MAT-POS-e10a589d-1

OCCn1c(CSc2nc3ccccc3o2)nc2ccc(Cl)cc21

CN(C)S(=O)(=O)c1cccc(C(=O)Nc2c(-c3ccccc3)nc3sccn23)c1

MAT-POS-e10a589d-2
Duplicate of:
TAT-ENA-80bfd3e5-1

CN(C)S(=O)(=O)c1cccc(C(=O)Nc2c(-c3ccccc3)nc3sccn23)c1

CS(=O)(=O)c1oc(-c2ccc(F)cc2)nc1S(=O)(=O)c1ccc(Cl)cc1

MAT-POS-e10a589d-3
Duplicate of:
LON-WEI-ff7b210a-2

CS(=O)(=O)c1oc(-c2ccc(F)cc2)nc1S(=O)(=O)c1ccc(Cl)cc1

N#Cc1ncn(CC(=O)Nc2ccc(Br)cc2Cl)n1

MAT-POS-e10a589d-4

N#Cc1ncn(CC(=O)Nc2ccc(Br)cc2Cl)n1

3-aminopyridine-like Assayed Check Availability on Manifold View
CCn1c(CSc2nc(C)c(C)n2CC2CCCO2)nc2cc(S(=O)(=O)N(C)C)ccc21

MAT-POS-e10a589d-5
Duplicate of:
LON-WEI-ff7b210a-10

CCn1c(CSc2nc(C)c(C)n2CC2CCCO2)nc2cc(S(=O)(=O)N(C)C)ccc21


Design Rationale:

Hits from Weizmann HTS that are available from Enamine as screening compounds

Discussion: