Submission Details
Molecule(s):
CC(=O)NCCc1c[nH]c2c(CCNS(C)(=O)=O)cc(F)cc12
CC(=O)NCCc1c[nH]c2c(CCNS(C)(=O)=O)cccc12
CC(=O)N1CCc2c([nH]c3c(CCNS(C)(=O)=O)cccc23)C1
CS(=O)(=O)NCCc1cccc2c3c([nH]c12)CN(S(C)(=O)=O)CC3
CS(=O)(=O)NCCc1c[nH]c2c(CCNS(C)(=O)=O)cccc12
NS(=O)(=O)c1cc2cc(F)ccc2[nH]1
Design Rationale:
Merging by eye of non-covalent fragments evolved with rational design to reduce flexibility.