Submission Details

Molecule(s):
O=C(CCl)N1CC2CC1CN2Cc1cc(O)ccc1O

MAK-UNK-df1a028e-1

O=C(CCl)N1CC2CC1CN2Cc1cc(O)ccc1O

piperazine-chloroacetamide Check Availability on Manifold View
Cc1cc(C)c(C)c(S(=O)(=O)N2CC3CC2CN3C(=O)c2cc(=O)[nH]c3ccccc23)c1C

MAK-UNK-df1a028e-2

Cc1cc(C)c(C)c(S(=O)(=O)N2CC3CC2CN3C(=O)c2cc(=O)[nH]c3ccccc23)c1C

O=C(c1cc(=O)[nH]c2ccccc12)N1CC2CC1CN2c1ccccc1

MAK-UNK-df1a028e-3

O=C(c1cc(=O)[nH]c2ccccc12)N1CC2CC1CN2c1ccccc1

CC(CCc1ccccc1)N1CC2CC1CN2C(=O)CCl

MAK-UNK-df1a028e-4

CC(CCc1ccccc1)N1CC2CC1CN2C(=O)CCl

piperazine-chloroacetamide Check Availability on Manifold View
Cc1ccc(S(=O)(=O)NC2CC3CC2CN3C(=O)CCl)cc1

MAK-UNK-df1a028e-5

Cc1ccc(S(=O)(=O)NC2CC3CC2CN3C(=O)CCl)cc1

O=C(CCl)N1CC2CC1CN2Cc1cc(O)cc(Cl)c1

MAK-UNK-df1a028e-6

O=C(CCl)N1CC2CC1CN2Cc1cc(O)cc(Cl)c1

piperazine-chloroacetamide Check Availability on Manifold View
CS(=O)(=O)N1C2CC(C1c1ccccc1)N(C(=O)CCl)C2

MAK-UNK-df1a028e-7

CS(=O)(=O)N1C2CC(C1c1ccccc1)N(C(=O)CCl)C2

piperazine-chloroacetamide Check Availability on Manifold View
O=C(CCl)N1CC2CC1CN2Cc1cc(Cl)cc(Cl)c1

MAK-UNK-df1a028e-8

O=C(CCl)N1CC2CC1CN2Cc1cc(Cl)cc(Cl)c1

piperazine-chloroacetamide Check Availability on Manifold View
O=C(CCl)N1CC2CC1CN2C(c1ccccc1)c1ccccc1

MAK-UNK-df1a028e-9

O=C(CCl)N1CC2CC1CN2C(c1ccccc1)c1ccccc1

piperazine-chloroacetamide Check Availability on Manifold View

Design Rationale:

inspired by DAN-LON-a5fc619e-8, built from the recent (May 28) successful activity data for chloroacetamides; x0770 is a placeholder

Inspired By:
Discussion: