Submission Details

Molecule(s):
C#CCN(C)C(=O)C(CCc1ccccc1)NC(=O)C1CC(O)CN1C(=O)OCc1ccccc1

VAL-ASS-db6a4353-1

C#CCN(C)C(=O)C(CCc1ccccc1)NC(=O)C1CC(O)CN1C(=O)OCc1ccccc1


Design Rationale:

Bacherikov, V. A., Chittiboyina, A. G., & Avery, M. A. (2017). Design, Synthesis, and Biological Evaluation of Peptidomimetic N -Substituted Cbz-4-Hyp-Hpa-Amides as Novel Inhibitors of Plasmodium falciparum . Chemistry & Biodiversity, 14(8), e1700037. doi:10.1002/cbdv.201700037

Discussion: