Submission Details

JAN-GHE-d851b096
Molecule(s):
C=CC(=O)NN(C(=O)Cc1cccc(Cl)c1)c1cnccc1C

JAN-GHE-d851b096-1

C=CC(=O)NN(C(=O)Cc1cccc(Cl)c1)c1cnccc1C

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cccc(Cl)c1)C(c1cccnc1)N1C(=O)C=CC1=O

JAN-GHE-d851b096-2

O=C(Nc1cccc(Cl)c1)C(c1cccnc1)N1C(=O)C=CC1=O

C=CC(=O)N(c1ccc(NC(C)=O)cc1)N(C(=O)Nc1cccc(Cl)c1)c1cccnc1

JAN-GHE-d851b096-3

C=CC(=O)N(c1ccc(NC(C)=O)cc1)N(C(=O)Nc1cccc(Cl)c1)c1cccnc1

3-aminopyridine-like Check Availability on Manifold View
C=CC(=O)N(c1ccc(NC(C)=O)cc1)[C@@H](C(=O)Nc1cccc(Cl)c1)c1cccnc1

JAN-GHE-d851b096-4

C=CC(=O)N(c1ccc(NC(C)=O)cc1)[C@@H](C(=O)Nc1cccc(Cl)c1)c1cccnc1

C=CC(=O)N1CC[C@@H](C2CCCCC2)C(=O)N1c1cccnc1

JAN-GHE-d851b096-5

C=CC(=O)N1CC[C@@H](C2CCCCC2)C(=O)N1c1cccnc1

3-aminopyridine-like Check Availability on Manifold View
Cc1ccncc1Cn1ccccc1=O

JAN-GHE-d851b096-6

Cc1ccncc1Cn1ccccc1=O

C=CC(=O)N(c1cc(C(F)(F)F)on1)C(C(=O)NC1CCCCC1)c1cccnc1

JAN-GHE-d851b096-7

C=CC(=O)N(c1cc(C(F)(F)F)on1)C(C(=O)NC1CCCCC1)c1cccnc1

C=CC(=O)N(c1cccc(Cl)c1)C(C(=O)NC(C)(C)C)c1cccnc1

JAN-GHE-d851b096-8

C=CC(=O)N(c1cccc(Cl)c1)C(C(=O)NC(C)(C)C)c1cccnc1

C=CC(=O)N(c1cccc(Cl)c1)C(C(=O)Nc1cccc(Cl)c1)c1cccnc1

JAN-GHE-d851b096-9

C=CC(=O)N(c1cccc(Cl)c1)C(C(=O)Nc1cccc(Cl)c1)c1cccnc1

Design Rationale:

Based on the first assay results from submissions LON-WEI-b8d98729 and TRY-UNI-714a760b

Inspired By:
Discussion:

Contributor: Jan, Ghent University - Fri, 08 May 2020 12:37:49 +0000