Submission Details
Molecule(s):
CC(Cl)C(=O)N1CCC(C(=O)N2CCCCC2)CC1
Design Rationale:
add methyl group to Mpro-x1380 to reduce reactivity of alpha chloro amide, increase selectivity, and increase potency by extending toward prime side of active site
CC(Cl)C(=O)N1CCC(C(=O)N2CCCCC2)CC1
add methyl group to Mpro-x1380 to reduce reactivity of alpha chloro amide, increase selectivity, and increase potency by extending toward prime side of active site