Submission Details

SHR-UNK-cde60afe

Molecule(s):

CC(=O)NCCc1c[nH]c2c(C(=O)Cc3c[nH]c4ncccc34)c(CCNS(C)(=O)=O)ccc12

SHR-UNK-cde60afe-1

CC(=O)NCCc1c[nH]c2c(C(=O)Cc3c[nH]c4ncccc34)c(CCNS(C)(=O)=O)ccc12

Check Availability on Manifold View

Design Rationale:

I looked to find fragments that filled docking site 1 and I combined them to make a larger molecule.

Inspired By:

CC(=O)NCCc1c[nH]c2ccc(F)cc12

AAR-POS-d2a4d1df-2

CS(=O)(=O)NCCc1ccccc1

AAR-POS-d2a4d1df-1

CN1CCN(C(=O)Cc2c[nH]c3ncccc23)CC1

AAR-POS-d2a4d1df-20

Discussion:

Contributor: Shreyas Srinivasan - Thu, 02 Jul 2020 21:38:03 +0000