Submission Details
Molecule(s):
Cc1nc(CN2C(=O)C(=O)c3cc(Br)ccc32)cs1
CCCCN1C(=O)C(=O)c2cc(Br)cc(C)c21
CC(C)CCN1C(=O)C(=O)c2cc(Br)ccc21
CCc1ccc2c(c1)C(=O)C(=O)N2CC(=O)O
O=C(O)CN1C(=O)C(=O)c2cc([N+](=O)[O-])ccc21
O=C1C(=O)N(Cc2ccccc2)c2ccc([N+](=O)[O-])cc21
Design Rationale:
These compounds have been chosen to further explore the SAR around our previous submissions: LOR-NEU-c8f11034 and LOR-NOR-30067bb9. The suggested compounds are commercially available from Enamine and have been ordered for testing.
Other Notes:
Z229837880=NEU-0006911=AA-001 Z56793418=NEU-0006912=AA-001 Z330905748=NEU-0006913=AA-001 Z111504232=NEU-0006914=AA-001 Z324552784=NEU-0006915=AA-001 Z352251436=NEU-0006916=AA-001