Submission Details
Molecule(s):
CC(C)(C)C(=O)C(C#N)C(=O)Nc1ccc(Cl)cc1
N#C/C(C(=O)Nc1ccc(F)cc1)=C(/O)c1ccc(Cl)cc1
N#CC(C(=O)Nc1ccccc1)C(=O)c1cccs1
N#CC(C(=O)Nc1ccccc1)C(=O)c1cccc(Cl)c1
N#CC(C(=O)Nc1cccc(Cl)c1)C(=O)c1cccs1
Cc1cccc(NC(=O)C(C#N)C(=O)C2CCCC2)c1
Cc1cccc(NC(=O)C(C#N)C(=O)C2CCC2)c1
Cc1cccc(NC(=O)C(C#N)C(=O)C2CC2)c1
CCCSCC(=O)C(C#N)C(=O)Nc1ccccc1F
CCCSCC(=O)C(C#N)C(=O)Nc1ccc(F)cc1F
Cc1ccc(NC(=O)C(C#N)C(=O)CC(C)C)cc1
CC(C)(C)CC(=O)C(C#N)C(=O)Nc1ccccc1
Cc1cccc(NC(=O)C(C#N)C(=O)CC(C)C)c1
CCC(CC)C(=O)C(C#N)C(=O)Nc1ccc(F)cc1
N#C/C(C(=O)NCc1ccccc1)=C(/O)CCl
C/C(O)=C(\C#N)C(=O)Nc1ccc(C(F)(F)F)cc1
C/C(O)=C(\C#N)C(=O)Nc1ccc(S(F)(F)(F)(F)F)cc1
Cc1oncc1C(=O)Nc1ccc(C(F)(F)F)cc1
Design Rationale:
Related to Leflunomide and analogues as per a previous mail. SF5 analogue is made in our lab as part of a PhD programme so I can source this. (sorry, couldn't access the fragments so picked one at random below!)
Other Notes:
Available and would possibly be free from eMolecules.