Submission Details

Molecule(s):
O=C1CN(C(=O)Cc2cccc(Cl)c2)Cc2ccccc21

EDJ-MED-c292668a-1

O=C1CN(C(=O)Cc2cccc(Cl)c2)Cc2ccccc21

O=C1CN(C(=O)C2CNC(=O)C3C=CC(Cl)=CC32)Cc2ccccc21

EDJ-MED-c292668a-2

O=C1CN(C(=O)C2CNC(=O)C3C=CC(Cl)=CC32)Cc2ccccc21

O=C1CN(C(=O)C2COCC3C=CC(Cl)=CC32)Cc2ccccc21

EDJ-MED-c292668a-3

O=C1CN(C(=O)C2COCC3C=CC(Cl)=CC32)Cc2ccccc21


Design Rationale:

Tetralone replacements for isoquinoline from Robert Glen

Discussion: