Submission Details
Molecule(s):
Cc1nc(CN(C)C(=O)NCC#N)cs1
CC(C)(C#N)OCc1ccccc1
N#C[C@@H](N)C1CCOCC1
C#CCN(CC#N)S(=O)(=O)c1ccccc1
CC(C)[C@H](NCC#N)C(=O)N1CCOCC1
CC(NCc1ccc(C#N)cc1)C1CCOC1
CC(C)(C#N)N1CCOCC1
N#CC12CC3CC(CC(C3)C1)C2
N#CCC1(O)CCOCC1
N#CC(N)C1CCOC1
N#CC1(O)CC2CCC1C2
Design Rationale:
Enamine Terminal Acetylene Fragment Set, changed triple bond into nitrile, ranked by antiviral properties at https://molmatinf.com/covid19/