Submission Details

JOK-SYG-b9f02a42
Molecule(s):
CNCc1cc(CN2CCN(C(=O)CCl)CC2)c2[nH]cc(CCNC(C)=O)c2c1

JOK-SYG-b9f02a42-1

CNCc1cc(CN2CCN(C(=O)CCl)CC2)c2[nH]cc(CCNC(C)=O)c2c1

piperazine-chloroacetamide Check Availability on Manifold View
CNCCc1cc(CN2CCN(C(=O)CCl)CC2)c2[nH]cc(CCNC(C)=O)c2c1

JOK-SYG-b9f02a42-2

CNCCc1cc(CN2CCN(C(=O)CCl)CC2)c2[nH]cc(CCNC(C)=O)c2c1

piperazine-chloroacetamide Check Availability on Manifold View
COCCc1cc(CN2CCN(C(=O)CCl)CC2)c2[nH]cc(CCNC(C)=O)c2c1

JOK-SYG-b9f02a42-3

COCCc1cc(CN2CCN(C(=O)CCl)CC2)c2[nH]cc(CCNC(C)=O)c2c1

piperazine-chloroacetamide Check Availability on Manifold View
Design Rationale:

770+104+possible interaction with Asp187

Inspired By:
Discussion:

Contributor: Jokin Carrillo Arregui, Sygnature Discovery - Mon, 25 May 2020 19:59:43 +0000