Submission Details
Molecule(s):
O=C1C(=O)N(Cc2ncon2)c2ccc(-c3cccc(Cl)c3)cc21
COC(=O)c1cc(-c2cccc(Cl)c2)cc2c1NC(=O)C2=O
COC(=O)c1cc(-c2cccc(Cl)c2)cc2c1N(Cc1ncon1)C(=O)C2=O
O=C1CC(Oc2cc(Cl)cc(-c3ccc4c(c3)C(=O)C(=O)N4Cc3ncon3)c2)N1
O=C1CC(Oc2cc(Cl)cc(-c3ccc4c(c3)C(=O)C(=O)N4)c2)N1
N#Cc1cncc(-c2ccc3c(c2)C(=O)C(=O)N3Cc2ncon2)c1
N#Cc1cncc(-c2ccc3c(c2)C(=O)C(=O)N3)c1
N#Cc1cccc(CN2C(=O)C(=O)c3cc(-c4cncc(C#N)c4)ccc32)c1
N#Cc1cccc(CN2C(=O)C(=O)c3cc(-c4cccc(Cl)c4)ccc32)c1
Design Rationale:
Expansion of isatin hits by merging with other hits in Fragalysis.