Submission Details

Molecule(s):
Cc1c(Cl)cccc1CC(=O)Nc1cncc2ccccc12

MAT-POS-afd4d4fd-1

Cc1c(Cl)cccc1CC(=O)Nc1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cccc(Cl)n1)Nc1cncc2ccccc12

MAT-POS-afd4d4fd-2

O=C(Cc1cccc(Cl)n1)Nc1cncc2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1Cl)Nc1cncc2ccccc12

MAT-POS-afd4d4fd-3

O=C(Cc1cccc(Cl)c1Cl)Nc1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View

Design Rationale:

Analogs of EDJ-MED-e4b030d8-8, 9, 10 lacking the pyran rings for ease of synthesis.

Discussion: