Submission Details
Molecule(s):
O=C(CN1Cc2ccc(Cl)cc2[C@@]2(CCN(c3cncc4ccccc34)C2=O)C1)NCC(F)(F)F
Design Rationale:
close amide analog of highly active, low clearance molecules like CVD-20299 and other simple amide. CF3 ET will reduce electron density of the amide, may have lower efflux