Submission Details

Molecule(s):
O=c1[nH]c(Cc2cccc(C(F)(F)F)c2)nc2cnccc12

JOH-UNI-abfda500-1
Duplicate of:
JOH-UNI-61f30276-2

O=c1[nH]c(Cc2cccc(C(F)(F)F)c2)nc2cnccc12

O=c1[nH]c(Cc2cccc(S(F)(F)(F)(F)F)c2)nc2cnccc12

JOH-UNI-abfda500-2
Duplicate of:
JOH-UNI-61f30276-3

O=c1[nH]c(Cc2cccc(S(F)(F)(F)(F)F)c2)nc2cnccc12

COc1ccccc1OCCNC(=O)c1cc(N)cc2ccccc12

JOH-UNI-abfda500-3
Duplicate of:
DAR-DIA-8e329c92-2

COc1ccccc1OCCNC(=O)c1cc(N)cc2ccccc12

O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(=O)O

JOH-UNI-abfda500-4

O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(=O)O

3-aminopyridine-like Assayed Check Availability on Manifold View
NC(=O)c1ccncc1NC(=O)Cc1cccc(Cl)c1

JOH-UNI-abfda500-5
Duplicate of:
ANN-UNI-98d2bf15-3

NC(=O)c1ccncc1NC(=O)Cc1cccc(Cl)c1

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1ccncc1NC(=O)Cc1ccccc1N

JOH-UNI-abfda500-6
Duplicate of:
ANN-UNI-98d2bf15-1

Cc1ccncc1NC(=O)Cc1ccccc1N

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(C(F)(F)F)c1)Nc1cnccc1C(=O)O

JOH-UNI-abfda500-7

O=C(Cc1cccc(C(F)(F)F)c1)Nc1cnccc1C(=O)O

3-aminopyridine-like Assayed Check Availability on Manifold View

Design Rationale:

Sorry, long overdue compounds. Delay, a consequence of the pandemic, social distancing etc but we got there in the end and these might "plug a gap" in the SAR.

Discussion: