Molecule Details

CN(C)C/C=C/C(=O)NCc1c[nH]c2ccccc12
Assayed
Molecular Properties
SMILES:
CN(C)C/C=C/C(=O)NCc1c[nH]c2ccccc12
MW: 257.337
Fraction sp3: 0.27
HBA: 2
HBD: 2
Rotatable Bonds: 5
TPSA: 48.13
cLogP: 1.9019
Covalent Warhead:
Covalent Fragment:
Activity Data
Average Inhibition @ 20 µM - Fluorescence: 3.862392
Average Inhibition @ 50 µM - Fluorescence: 0.7435621
Relative Solubility @ 20 µM: 0.96
Relative Solubility @ 100 µM: 0.98
Order Status
Ordered: 2020-04-17
Synthesis Location: enamine
Shipped: 2020-05-20

Activated double bonds (2)

vinyl michael acceptor1

CC(=O)NCCc1c[nH]c2ccc(F)cc12

AAR-POS-d2a4d1df-2

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CN(C)C/C=C/C(=O)Nc1c[nH]c2ccccc12

ANT-OPE-ab37bd51-1
0.535

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CC(=O)NCCc1c[nH]c2ccccc12

SAN-PRS-3c4a6997-2
0.423

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CN(C)CCc1c[nH]c2ccccc12

JOH-MSK-a63bdd1d-10
0.418

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O=C(O)CNC(=O)Cc1c[nH]c2ccccc12

MAR-UCB-195bc32d-22
0.417

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O=C(Cc1c[nH]c2ccccc12)Nc1ccccc1

CUN-WAB-25b584ee-2
0.392

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CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1ccccc1

NIC-BIO-3276ca7f-7
0.381

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CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC#CBr

NIC-BIO-3276ca7f-2
0.376

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O=C(O)CC(NC(=O)Cc1c[nH]c2ccccc12)C(=O)O

MAR-UCB-195bc32d-9
0.372

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CC(C(=O)O)N(C(=O)Cc1c[nH]c2ccccc12)c1cncnc1

MAR-TRE-85681e92-68
0.365

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CN(c1cncnc1)C(Cc1c[nH]c2ccccc12)C(=O)O

MAR-TRE-85681e92-33
0.357

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CCNc1ncc(C#N)cc1NCc1c[nH]c2ccccc12

GAB-REV-df64cf17-18
0.352

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NC(CO)Cc1c[nH]c2ccccc12

MAR-UCB-195bc32d-18
0.347

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Cn1ccn(C(Cc2c[nH]c3ccccc23)C(=O)O)c1=[Au+]Cl

MAR-TRE-4f39ef4a-5
0.345

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Cc1ccc(S(=O)(=O)NC(=O)NCCc2c[nH]c3ccccc23)cc1

MAR-TRE-fd17a9b8-35
0.341

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CC(C)C(C(=O)O)N(C(=O)Cc1c[nH]c2ccccc12)c1cncnc1

MAR-TRE-85681e92-53
0.341

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CC(CNC(=O)C(C)Cc1c[nH]c2ccccc12)Cc1ccccc1

CUN-WAB-25b584ee-1
0.341

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COc1ccc(N(Cc2ccccc2)C(=O)Cc2c[nH]c3ccccc23)cc1

ALP-POS-a3de0cb1-15
0.341

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CCC(C)C(C(=O)O)N(C(=O)Cc1c[nH]c2ccccc12)c1cncnc1

MAR-TRE-85681e92-69
0.341

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O=C(O)C(Cc1c[nH]c2ccccc12)Nc1ncccn1

MAR-TRE-f5c2d31c-47
0.337

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COC(=O)C(Cc1c[nH]c2ccccc12)n1ccn(C)c1=[Au+]Cl

MAR-TRE-4f39ef4a-9
0.333

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CC(=O)NCc1c[nH]c2ccc(C#N)cc12

SCO-VAN-260d9628-5
0.329

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CC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)Nc1cccnc1

MAR-TRE-74c6519b-79
0.326

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CC(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CO)C(=O)N[C@@H](CCCNC(N)=O)C(N)=O

SAL-INS-68b48d12-10
0.324

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COc1ccc(N(Cc2ccoc2)C(=O)Cc2c[nH]c3ccccc23)cc1

ALP-POS-8ed8d9ec-2
0.323

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O=C(Cn1c(=O)[nH]c2ccccc2c1=O)NCCc1c[nH]c2ccccc12

MAR-TRE-fd17a9b8-10
0.323

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COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1cncnc1

MAR-TRE-4f781e27-69
0.322

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CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1cncnc1

MAR-TRE-4f781e27-6
0.319

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CCN(Cc1ccc(OC)c(F)c1)C(=O)C(Cc1c[nH]c2ccccc12)NC(C)=O

NJA-MAN-b9fb953f-5
0.311

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CC(C)CC(NC(=O)Cc1c[nH]c2ccccc12)C(=O)Oc1csc(CCl)n1

MAR-TRE-36bf7dba-27
0.307

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CC(Cc1c[nH]c2ccccc12)C(=O)NCC(C)C(Cc1ccccc1)c1ccccc1

SUN-WAB-e274cdaf-1
0.306

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Cc1nc(NCC2CCCO2)sc1C(=O)NCCc1c[nH]c2ccccc12

MAR-TRE-fd17a9b8-25
0.306

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CCC(C)C(NC(=O)Cc1c[nH]c2ccccc12)C(=O)Oc1csc(CCl)n1

MAR-TRE-36bf7dba-21
0.304

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CC(C)C(NC(=O)Cc1c[nH]c2ccccc12)C(=O)Oc1csc(CCl)n1

MAR-TRE-36bf7dba-26
0.303

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CC(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCNC(N)=O)C(N)=O

SAL-INS-68b48d12-8
0.303

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CC(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=O)C(N)=O

SAL-INS-68b48d12-6
0.300

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CC(C)Cn1cc(NC(=O)NCCc2c[nH]c3ccccc23)c2ccccc2c1=O

LON-WEI-4d77710c-20
0.297

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O=C(Cc1c[nH]c2ccccc12)N(Cc1ccccc1)c1ccc(N2CCOCC2)cc1

ALP-POS-8ed8d9ec-6
0.297

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N[C@H](Cc1c[nH]c2ccccc12)C(=O)NN(Cc1ccccc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)O

YIA-UNI-71f25a82-1
0.294

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CC(C)n1ncc2cc(NC(=O)CCc3c[nH]c4ccccc34)cnc21

MAR-TRE-b77b7921-67
0.294

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N=C(N)NCCC[C@H](NC(=O)[C@@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CO)C(=O)O

SAL-INS-68b48d12-9
0.292

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O=C(Cc1csc(-c2ccccc2F)n1)NCCc1c[nH]c2ccccc12

MAR-TRE-fd17a9b8-18
0.290

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O=C(CCl)N1CCN(c2c(F)cc(N(CC3CC3)C(=O)Cc3c[nH]c4ccccc34)cc2F)CC1

NIM-UNI-310206f0-31
0.290

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O=C(N[C@H]1CCN2C(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H]12)c1ccccc1

BRU-UNI-248b30bc-12
0.286

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CC(C)C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CN(N)Cc1ccccc1)C(=O)O

YIA-UNI-71f25a82-2
0.283

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Nc1nc2c(s1)CN(C(=O)CCc1c[nH]c3ccccc13)CC2

MAT-POS-ea426761-94
0.277

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N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CO)C(=O)O

SAL-INS-68b48d12-5
0.277

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C=CC(=O)N1CC(NCc2c[nH]c3ccc(C#N)cc23)C1

JAN-GHE-c863d918-1
0.277

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O=C(NCC(=O)c1c[nH]c2ccccc12)c1cncnc1

MAR-TRE-4f781e27-96
0.276

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N=C(N)NCCC[C@H](NC(=O)CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CO)C(=O)O

SAL-INS-68b48d12-7
0.273

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O=C(Nc1cccnc1)[C@H]1CCCN(C(=O)CCc2c[nH]c3ccccc23)C1

MAR-TRE-f6f5f473-6
0.266

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O=C(CCl)N1CCN(c2c(F)cc(N(C(=O)Cc3c[nH]c4ccccc34)c3ncccn3)cc2F)CC1

NIM-UNI-310206f0-49
0.266

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COCCN1C(=O)[C@@H]2C(Cc3c[nH]c4ccccc34)NC3(C(=O)Nc4ccc(Cl)cc43)[C@@H]2C1=O

AAR-POS-fca48359-10
0.259

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COCCN1C(=O)[C@@H]2[C@H](Cc3c[nH]c4ccccc34)N[C@]3(C(=O)Nc4ccc(Cl)cc43)[C@@H]2C1=O

FAR-UNI-736b943a-8
0.259

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Cc1ccncc1NC(=O)CNc1c[nH]c2ccccc12

GAB-REV-70cc3ca5-17
0.258

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CN(C)CCc1c[nH]c2cccc(OP(=O)(O)O)c12

MAR-UCB-195bc32d-5
0.256

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CC(=O)NCCc1c[nH]c2ccc(C#N)cc12

JOH-MEM-4bb7e4cc-1
0.256

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CC(=O)NCCc1c[nH]c2ccc(C#N)cc12

MAT-GIT-deadff56-1
0.256

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CC(=O)NCCc1c[nH]c2ccc(C#N)cc12

DUN-NEW-f8ce3686-12
0.256

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O=C(NCc1cc(=O)[nH]c2ccccc12)c1cncnc1

MAR-TRE-92684b97-53
0.256

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CCOC(=O)C(NC(=O)c1cncnc1)c1c[nH]c2ccccc12

MAR-TRE-66ac689e-52
0.255

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O=C(NCCNC(=O)C1CCCO1)c1c[nH]c2ccccc12

MAR-TRE-fd17a9b8-29
0.255

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NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H]1CN(C(=O)c2cccc(F)c2)CCN1C(=O)N1CCOCC1

BRU-UNI-248b30bc-8
0.254

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CC(=O)N[C@@H](Cc1c[nH]c2ncccc12)C(=O)NCc1ccccc1

NIC-BIO-3276ca7f-4
0.250

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O=C(CNC(=O)c1c[nH]c2ccccc12)Nc1cccnc1

MAR-TRE-74c6519b-68
0.247

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CC(C)N(C(=O)Cc1c(O)c2ccccc2[nH]c1=O)C(C)C

LON-WEI-4d77710c-3
0.247

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CNCc1c[nH]c2ccc(F)cc12

DAR-DIA-eace69ff-36
0.247

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CNCc1c[nH]c2ccc(Cl)cc12

DAR-DIA-eace69ff-37
0.247

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O=C(Cn1c(=O)[nH]c2ccccc2c1=O)NCCc1c[nH]c2ccc(Cl)cc12

MAR-TRE-fd17a9b8-1
0.245

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CC(C)(C)c1cc(C(C)(C)C)c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O

MAR-UCB-195bc32d-45
0.242

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O=C(O)NC(=O)Cc1c[nH]c2ccc(F)cc12

ABI-SAT-30e287c1-2
0.241

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COc1cc(CNC(=O)Cc2ncc[nH]2)c2ccccc2n1

BAR-COM-4e090d3a-22
0.240

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CN(C)CCc1c[nH]c2ccc(S(N)(=O)=O)cc12

ANT-OPE-47f3bb65-4
0.238

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CC(=O)NCCc1c[nH]c2ccc(O)cc12

MAR-UCB-195bc32d-16
0.238

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CC(=O)NCCc1c[nH]c2ccc(O)cc12

JOH-MSK-a63bdd1d-4
0.238

View
CN(C)CCc1c[nH]c2ccc(O)cc12

MAR-UCB-195bc32d-19
0.237

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CN(C)CCc1c[nH]c2ccc(O)cc12

JOH-MSK-a63bdd1d-9
0.237

View
O=C(NCC(c1ccccc1)c1c[nH]c2ccccc12)c1cncnc1

MAR-TRE-9d18ae8c-91
0.237

View
CC(=O)N[C@@H](Cc1c[nH]c2ncccc12)C(=O)NCC#CBr

NIC-BIO-3276ca7f-1
0.237

View
C/C1=C/[C@@H](C)C/C=C\[C@H]2[C@@H]3O[C@]3(C)[C@@H](C)[C@H]3[C@H](Cc4c[nH]c5ccccc45)NC(=O)[C@@]23C(=O)/C=C\C(=O)[C@@H]1O

BRU-UNI-248b30bc-19
0.236

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CC(=O)NCCc1c[nH]c2ccc(F)cc12

AAR-POS-d2a4d1df-2
0.235

View
CC(=O)N[C@@H](Cc1c[nH]c2ncccc12)C(=O)NCc1cccc(Cl)c1

NIC-BIO-3276ca7f-6
0.235

View
CC(=O)NCCc1c[nH]c2ccc(Cl)cc12

SAN-PRS-3c4a6997-1
0.235

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CC(O)CNCc1nc2ccccc2[nH]1

MAK-UNK-3ae66343-1
0.235

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C=CC(=O)N1CCN(Cc2ccc(CNC(=O)CNCc3c[nH]c4ccc(F)cc34)cc2)CC1

MAK-UNK-10dfa458-15
0.234

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O=CCc1c[nH]c2ccc(O)cc12

JOH-MEM-5e386bbd-7
0.234

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COc1cccc(C(CNC(=O)c2cncnc2)c2c[nH]c3ccccc23)c1OC

MAR-TRE-92684b97-10
0.234

View
COc1ccc(C2C(O)C(c3c[nH]c4ccccc34)=NN2C(=O)CCl)cc1

TAT-ENA-80bfd3e5-16
0.233

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Cn1c(O)c(CNC(N)=O)c2ccccc21

SAN-PRS-3c4a6997-10
0.232

View
CN(C)C/C=C/C(=O)N1Cc2ccccc2C(c2ccccc2)C1

REN-UFA-aaaed2d6-1
0.232

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CC(=O)NCc1c[nH]c2c(Cc3nnc(C)s3)cc(F)cc12

SCO-VAN-260d9628-7
0.232

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CC(=O)NCCc1c[nH]c2c(CNC(=O)CCl)cccc12

DUN-NEW-f8ce3686-21
0.231

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O=C(NC(C(=O)O)c1c[nH]c2ccccc12)c1cncnc1

MAR-TRE-8190bb11-25
0.231

View
CC(=O)NCCc1c[nH]c2c(Cc3nc4ccccc4[nH]3)cc(F)cc12

GAB-REV-4a4e2ff3-3
0.231

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CC(=O)N[C@@H](Cc1c[nH]c2ncccc12)C(=O)NCc1ccc(Cl)cc1

NIC-BIO-3276ca7f-5
0.230

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CN(CC(=O)NCc1cccs1)S(=O)(=O)c1cccc2nsnc12

MAT-POS-b5746674-84
0.230

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COc1ccc2[nH]cc(CCNC(C)=O)c2c1

JOH-MSK-35a8745a-1
0.230

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CN(C)CCc1c[nH]c2ccc(CS(N)(=O)=O)cc12

ANT-OPE-47f3bb65-2
0.230

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COc1ccc2[nH]cc(CCNC(C)=O)c2c1

MAR-UCB-195bc32d-21
0.230

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COc1ccc2[nH]cc(CCNC(C)=O)c2c1

ALE-ACE-2610ee4d-1
0.230

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O=C1NC(Cc2c[nH]c3ccccc23)C(=O)N1c1ccc2[nH]c(C(F)F)nc2c1

IAN-BAS-8ad3d156-1
0.229

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CN(C)CC=CC(=O)NCCc1c[nH]c2ccccc12

0.800

View
CN(C)CC=CC(=O)NCCCc1c[nH]c2ccccc12

0.766

View
CN(C)CC=CC(=O)NCc1cccc2[nH]ccc12

0.723

View
CN(C)CC=CC(=O)NNC(=O)Cc1c[nH]c2ccccc12

0.708

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CN(C)CC=CC(=O)NCC(=O)c1c[nH]c2ccccc12

0.673

View
CN(C)CC=CC(=O)NCc1ccccc1CN(C)C

0.667

View
CN(C)CC=CC(=O)NCc1cccc2ccccc12

0.660

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CN(C)CC=CC(=O)NCc1ccccc1N(C)C

0.652

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Cc1ccc(CNC(=O)C=CCN(C)C)c2ccccc12

0.646

View
CN(C)CC=CC(=O)NC(CO)Cc1c[nH]c2ccccc12

0.642

View
CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C=CCN(C)C

0.642

View
CN(C)CC=CC(=O)NCc1cc2ccccc2[nH]c1=O

0.640

View
CN(C)CC=CC(=O)NNC(=O)c1c[nH]c2ccccc12

0.633

View
CN(C)CC=CC(=O)NCc1coc2ccccc12

0.633

View
CN(C)CC=CC(=O)NCc1cn(C)c2ccccc12

0.633

View
Cc1ccccc1CNC(=O)C=CCN(C)C

0.630

View
CN(C)CC=CC(=O)NCc1ccccc1CO

0.630

View
CCc1ccccc1CNC(=O)C=CCN(C)C

0.630

View
CN(C)CC=CC(=O)NCC(c1ccccc1)c1c[nH]c2ccccc12

0.623

View
CN(C)CC=CC(=O)NCc1csc2ccccc12

0.620

View
CN(C)CC=CC(=O)NCc1ccnc2ccccc12

0.620

View
COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C=CCN(C)C

0.618

View
COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)C=CCN(C)C

0.618

View
CN(C)CC=CC(=O)NCc1ccccc1Cl

0.617

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CN(C)CC=CC(=O)NCc1ccccc1F

0.617

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CN(C)CC=CC(=O)NCc1ccccc1Br

0.617

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CN(C)CC=CC(=O)NCc1ccccc1O

0.617

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CN(C)CC=CC(=O)NCc1ccc[nH]c1=O

0.617

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CC(C)c1ccccc1CNC(=O)C=CCN(C)C

0.617

View
CCN(CC)Cc1ccccc1CNC(=O)C=CCN(C)C

0.612

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CCN(C)c1ccccc1CNC(=O)C=CCN(C)C

0.612

View
CN(C)CC=CC(=O)NCc1cc2ccccc2[nH]1

0.612

View
COc1ccc(CNC(=O)C=CCN(C)C)c2ccccc12

0.608

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CCC=CC(=O)NCCc1c[nH]c2ccccc12

0.604

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Cc1ccc2[nH]cc(CCNC(=O)C=CCN(C)C)c2c1

0.604

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Cc1ccc2c(CCNC(=O)C=CCN(C)C)c[nH]c2c1

0.604

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CN(C)CC=CC(=O)NCc1ccccc1

0.600

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CN(CC=CC(=O)NCCc1c[nH]c2ccccc12)CC(F)(F)F

0.600

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CN(C)CC=CC(=O)NCc1ccccc1S(=O)(=O)N(C)C

0.600

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CC(C)N(C)Cc1ccccc1CNC(=O)C=CCN(C)C

0.600

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CN(C)CC=CC(=O)NCc1nc2ccccc2[nH]1

0.600

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CN(C)CC=CC(=O)NCc1nn(C)c2ccccc12

0.600

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CN(C)CC=CC(=O)NCc1ccccc1N1CCOCC1

0.596

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CN(C)CC=CC(=O)NCCc1cccc2[nH]ccc12

0.596

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CN(C)CC=CC(=O)NCCc1c[nH]c2ccc(Br)cc12

0.593

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CN(C)CC=CC(=O)NCCc1c[nH]c2ccc(Cl)cc12

0.593

View
CN(C)CC=CC(=O)NCCc1c[nH]c2cc(F)ccc12

0.593

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CN(C)CC=CC(=O)NCCc1c[nH]c2cc(Cl)ccc12

0.593

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COc1ccccc1CNC(=O)C=CCN(C)C

0.592

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COCc1ccccc1CNC(=O)C=CCN(C)C

0.592

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CN(C)CC=CC(=O)NCc1ccccc1C(C)(C)C

0.592

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CN(C)CC=CC(=O)NCc1ccccc1CS(C)(=O)=O

0.592

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CN(C)CC=CC(=O)NCC(c1ccccc1Cl)c1c[nH]c2ccccc12

0.589

View
CN(C)CC=CC(=O)NCc1ccccc1N1CCCC1

0.588

View
CN(C)CC=CC(=O)NCc1noc2ccccc12

0.588

View
CN(C)CC=CC(=O)NCc1cc(N(C)C)nc2ccccc12

0.585

View
Cc1ccc(CNC(=O)C=CCN(C)C)c(C)c1

0.583

View
Cc1cccc(CNC(=O)C=CCN(C)C)c1C

0.583

View
CN(C)CC=CC(=O)NCc1ccccc1C(F)(F)F

0.580

View
CCOc1ccccc1CNC(=O)C=CCN(C)C

0.580

View
CCC=CC(=O)NCCCc1c[nH]c2ccccc12

0.580

View
CN(C)CC=CC(=O)NCc1ccccc1S(C)(=O)=O

0.580

View
CC(=O)Nc1ccccc1CNC(=O)C=CCN(C)C

0.580

View
CN(C)Cc1ccccc1CNC(=O)Cc1c[nH]c2ccccc12

0.580

View
CN(C)CC=CC(=O)NCC(c1ccc(N(C)C)cc1)c1c[nH]c2ccccc12

0.579

View
CN(CC=CC(=O)NCCCc1c[nH]c2ccccc12)CC(F)(F)F

0.579

View
CN(C)CC=CC(=O)NCc1nccc2ccccc12

0.577

View
CN(C)CC=CC(=O)NCc1ccccc1N1CCCCC1

0.577

View
CN(C)CC=CC(=O)NCc1cccc2ncccc12

0.577

View
CN(C)CC=CC(=O)NCc1nc2ccccc2c(=O)[nH]1

0.577

View
Cc1occc1CNC(=O)C=CCN(C)C

0.574

View
CN(C)CC=CC(=O)NCc1ccc[nH]1

0.574

View
CN(C)CC=CC(=O)N1CCN(C(=O)Cc2c[nH]c3ccccc23)CC1

0.574

View
Cc1cccc2[nH]cc(CCNC(=O)C=CCN(C)C)c12

0.574

View
Cc1cccc2c(CCNC(=O)C=CCN(C)C)c[nH]c12

0.574

View
COc1ccc2[nH]cc(CCNC(=O)C=CCN(C)C)c2c1

0.571

View
CN(C)CC=CC(=O)NCc1cccc(=O)[nH]1

0.571

View
CN(C)CC=CC(=O)NCCCc1c[nH]c2ccc(F)cc12

0.571

View
CCCC=CC(=O)NCCc1c[nH]c2ccccc12

0.569

View
CN(C)C(=O)C=CC(=O)NCCc1c[nH]c2ccccc12

0.569

View
CN(C)CC=CC(=O)NCc1ccccc1[N+](=O)[O-]

0.569

View
CCOCc1ccccc1CNC(=O)C=CCN(C)C

0.569

View
COC(=O)c1ccccc1CNC(=O)C=CCN(C)C

0.569

View
CN(C)CC=CC(=O)NCc1ccccc1NS(C)(=O)=O

0.569

View
CN(C)CC=CC(=O)NCc1ccccc1Sc1ccccc1

0.569

View
COC(=O)Cc1ccccc1CNC(=O)C=CCN(C)C

0.569

View
Cc1oc2ccccc2c1CNC(=O)C=CCN(C)C

0.569

View
CN(C)CC=CC(=O)NCc1ccccc1S(N)(=O)=O

0.569

View
COc1cccc(C(CNC(=O)C=CCN(C)C)c2c[nH]c3ccccc23)c1OC

0.567

View
CN(C)CC=CC(=O)NCc1ccccc1CN1CCOCC1

0.566

View
Cc1[nH]c2ccccc2c1CCNC(=O)C=CCN(C)C

0.566

View
CN(C)CC=CC(=O)NCc1ccccc1N1CCN(C)CC1

0.566

View
COc1c(CNC(=O)C=CCN(C)C)oc2ccccc12

0.566

View
CN(C)CC=CC(=O)NCc1ccc(-c2nc3ccccc3[nH]2)cc1

0.564

View
CCc1cccc2c(CCNC(=O)C=CCN(C)C)c[nH]c12

0.564

View
COc1cc(CNC(=O)C=CCN(C)C)c2ccccc2n1

0.564

View
CN(C)CC=CC(=O)NCCc1c[nH]c2c(Cl)cccc12

0.564

View
CN(C)CC=CC(=O)NCCc1c[nH]c2ncccc12

0.564

View
CN(C)CC=CC(=O)NC(c1c[nH]c2ccccc12)C(Cl)(Cl)Cl

0.564

View
CN(C)CC=CC(=O)NCCc1c[nH]c2cccc(Br)c12

0.564

View
CCC(=O)NCc1c[nH]c2ccccc12

0.200

View
CN(C)C/C=C/C(=O)NCc1c[nH]c2cc(F)c(F)cc12

0.173

View
CCN(Cc1cccc2[nH]ccc12)C(=O)/C=C/CN(C)C

0.160

View
C(NCC1C2=C(C=CC=C2)NC=1)(=O)C

0.869

View
C(NCC1C2=C(C=CC=C2)NC=1)(=O)CC

0.849

View
C(NCC1C2=C(C=CC=C2)NC=1)(=O)CC=C

0.848

View
C(NCC1C2=C(C=CC=C2)NC=1)(=O)CN(C)C

0.836

View
C(NCC1C2=C(C=CC=C2)NC=1)(=O)CCC

0.830

View


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