Submission Details

BEN-DND-a88ffd65
Molecule(s):
CNC(=O)CNCc1ccc(Cl)cc1NC(=O)Nc1cncc2cc(F)ccc12

BEN-DND-a88ffd65-1

CNC(=O)CNCc1ccc(Cl)cc1NC(=O)Nc1cncc2cc(F)ccc12

3-aminopyridine-like Check Availability on Manifold View
N#CC1(CS(=O)(=O)NCc2ccc(Cl)cc2NC(=O)Nc2cncc3cc(F)ccc23)CC1

BEN-DND-a88ffd65-2

N#CC1(CS(=O)(=O)NCc2ccc(Cl)cc2NC(=O)Nc2cncc3cc(F)ccc23)CC1

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cc(Cl)ccc1CNS(=O)(=O)CCO)Nc1cncc2cc(F)ccc12

BEN-DND-a88ffd65-3

O=C(Nc1cc(Cl)ccc1CNS(=O)(=O)CCO)Nc1cncc2cc(F)ccc12

3-aminopyridine-like Check Availability on Manifold View
CNC(=O)c1ccc(Cl)cc1NC(=O)Nc1cncc2cc(F)ccc12

BEN-DND-a88ffd65-4

CNC(=O)c1ccc(Cl)cc1NC(=O)Nc1cncc2cc(F)ccc12

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2cc(F)ccc12)n1cnc(=O)c2ccc(Cl)cc21

BEN-DND-a88ffd65-5

O=C(Nc1cncc2cc(F)ccc12)n1cnc(=O)c2ccc(Cl)cc21

O=C(Nc1cncc2cc(F)ccc12)N1CCS(=O)(=O)c2ccc(Cl)cc21

BEN-DND-a88ffd65-6

O=C(Nc1cncc2cc(F)ccc12)N1CCS(=O)(=O)c2ccc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Some urea analogues of recent interesting actives

Discussion:

Contributor: Benjamin Perry, DNDi - Wed, 07 Jul 2021 13:54:00 +0000