Submission Details

Molecule(s):
NC1(C(=O)Nc2nncn2C2CC2)CCOc2ccccc21

BRU-THA-a358fbdd-1

NC1(C(=O)Nc2nncn2C2CC2)CCOc2ccccc21

3-aminopyridine-like Check Availability on Manifold View
CC1(C(=O)Nc2nncn2C2CC2)CCOc2ccccc21

BRU-THA-a358fbdd-2

CC1(C(=O)Nc2nncn2C2CC2)CCOc2ccccc21

3-aminopyridine-like Made Check Availability on Manifold View
O=C(Nc1nncn1C1CC1)C1CCOc2ccc(Br)cc21

BRU-THA-a358fbdd-3

O=C(Nc1nncn1C1CC1)C1CCOc2ccc(Br)cc21

3-aminopyridine-like Check Availability on Manifold View
CC1(C(=O)Nc2nncn2C2CC2)CCOc2ccc(Cl)cc21

BRU-THA-a358fbdd-4

CC1(C(=O)Nc2nncn2C2CC2)CCOc2ccc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
CC1(C)CC(C(=O)Nc2nncn2C2CC2)c2ccccc2O1

BRU-THA-a358fbdd-5
Duplicate of:
NAU-LAT-8502cac5-5

CC1(C)CC(C(=O)Nc2nncn2C2CC2)c2ccccc2O1

Duplicate 3-aminopyridine-like Made Check Availability on Manifold View
CN(C)C1(C(=O)Nc2nncn2C2CC2)CCOc2ccccc21

BRU-THA-a358fbdd-6

CN(C)C1(C(=O)Nc2nncn2C2CC2)CCOc2ccccc21

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1nncn1C1CC1)C1CCOc2c(F)cccc21

BRU-THA-a358fbdd-7

O=C(Nc1nncn1C1CC1)C1CCOc2c(F)cccc21

3-aminopyridine-like Assayed Check Availability on Manifold View

Design Rationale:

Designs following up on JAG-UCB-a3ef7265-20

Other Notes:

Submitted by Matt of PostEra, on Bruce's behalf

Discussion: