Submission Details

MIC-UNK-a28eba03
Molecule(s):
CN1CCN(C(=O)Cc2cncc3ccccc23)CC1(C)C

MIC-UNK-a28eba03-1

CN1CCN(C(=O)Cc2cncc3ccccc23)CC1(C)C

CN1CCN(C(=O)Cc2cncc3ccccc23)CC1

MIC-UNK-a28eba03-2

CN1CCN(C(=O)Cc2cncc3ccccc23)CC1

CC1(C)CCCN(C(=O)Cc2cncc3ccccc23)C1

MIC-UNK-a28eba03-3

CC1(C)CCCN(C(=O)Cc2cncc3ccccc23)C1

CC1(C)CCN(C(=O)Cc2cncc3ccccc23)CC1

MIC-UNK-a28eba03-4

CC1(C)CCN(C(=O)Cc2cncc3ccccc23)CC1

Design Rationale:

Quinolines were more potent than benzotriazole compounds, so I expect similiar pattern there. Tertiary carbon in TIM-INF-fd8b8e92-1 occupies area similar to tert-butyl groups in many of Ugi compounds, so maybe there is some potential for merging

Inspired By:
Discussion:

Contributor: Michal K - Thu, 03 Dec 2020 13:13:32 +0000