Submission Details

Molecule(s):
Cc1ccc2c(c1)[C@@H](C(=O)Nc1nncn1C1CC1)CCO2

EDG-MED-a20b5824-1

Cc1ccc2c(c1)[C@@H](C(=O)Nc1nncn1C1CC1)CCO2

3-aminopyridine-like Check Availability on Manifold View
O=C1N(c2nncn2C2CC2)CCO[C@@]12CCOc1ccc(Cl)cc12

EDG-MED-a20b5824-2

O=C1N(c2nncn2C2CC2)CCO[C@@]12CCOc1ccc(Cl)cc12

3-aminopyridine-like Check Availability on Manifold View

Design Rationale:

JAG-UCB-a3ef7265-20 ideas Cl to Me standard medchem spiromorpholine analog, potential easier synthesis and lower logP

Discussion: