Submission: TRY-UNI-2eddb1ff

TRY-UNI-2eddb1ff

Molecule(s):

TRY-UNI-2eddb1ff-1

Cc1ccncc1NC(=O)Cc1cncc(C#N)c1

3-aminopyridine-like Made Check Availability on Manifold View

TRY-UNI-2eddb1ff-2

Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

3-aminopyridine-like Assayed Check Availability on Manifold View

TRY-UNI-2eddb1ff-3

Cc1ccncc1NC(=O)C(C)c1cncc(Cl)c1

3-aminopyridine-like Made Check Availability on Manifold View

TRY-UNI-2eddb1ff-4
Duplicate of:
JAN-GHE-83b26c96-5

Cc1ccncc1NC(=O)[C@@H](C)c1cccc(Cl)c1

Duplicate 3-aminopyridine-like Ordered Check Availability on Manifold View

TRY-UNI-2eddb1ff-5
Duplicate of:
JAN-GHE-83b26c96-4

Cc1ccncc1NC(=O)[C@H](C)c1cccc(Cl)c1

Duplicate 3-aminopyridine-like Ordered Check Availability on Manifold View

TRY-UNI-2eddb1ff-6

Cc1ccncc1NC(=O)Cc1cc(C#N)cc(OC2CC(=O)N2)c1

3-aminopyridine-like Assayed Check Availability on Manifold View

TRY-UNI-2eddb1ff-7

Cc1ccncc1NC(=O)Cc1cc(Cl)cc(OC2CC(=O)N2)c1

3-aminopyridine-like Assayed Check Availability on Manifold View

TRY-UNI-2eddb1ff-8

Cc1ccncc1NC(=O)C(C)c1cc(Cl)cc(OC2CC(=O)N2)c1

3-aminopyridine-like Assayed Check Availability on Manifold View

Design Rationale:

The design of the molecules was done by superimposing the different fragments from the crystal structures (by eye). The reactions should be fairly easy urea formation or amide coupling all from readily available starting materials. Fragments used for the conception of the ideas are the following x2572, x2646, x2649, x2569, x2562,