Submission Details
Molecule(s):
O=c1c(Nc2cccc(Cl)c2)c(Nc2cncc3ccccc23)c1=O
Cc1ccncc1Nc1c(Nc2cccc(Cl)c2)c(=O)c1=O
O=c1c(Nc2cccc(Cl)c2)c(Nc2n[nH]c3ccccc23)c1=O
O=c1c(Oc2cccc(Cl)c2)c(On2nnc3ccccc32)c1=O
O=c1c(Nc2cccc(Cl)c2)c(-n2nnc3ccccc32)c1=O
O=c1c(NCc2cccc(Cl)c2)c(-n2nnc3ccccc32)c1=O
O=c1c(Nc2cccc(Cl)c2)c(Nn2nnc3ccccc32)c1=O
Cc1ccncc1N(C)c1c(Nc2cccc(Cl)c2)c(=O)c1=O
CN(c1cccc(Cl)c1)c1c(Nc2cncc3ccccc23)c(=O)c1=O
Design Rationale:
Squaramide as bioisoteric replacement for urea in aminopyridine/isoquinoline/benzotriazole series.