Submission Details

Design Rationale:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114104/ In conclusion, the compounds extracted from A. annua, L. radiata, P. lingua, and L. aggregata have been identified to show antiviral activity against SARS-CoV in Vero cell-based CPE/MTS screening. Further structure and activity study has determined that lycorine is an active component in the alkaloid portion of the herbal plant L. radiata. The results from our study provide strong support for the usage of these herbs to treat SARS-CoV infectious diseases. Our results also demonstrated that lycorine is a good candidate for the development of new antiviral medicine.