Submission Details

SEA-TRI-9e600f3c

Molecule(s):

C=C(Cc1ccno1)C(=O)N1CCN(Cc2cccc(Cl)c2)CC1

SEA-TRI-9e600f3c-1

C=C(Cc1ccno1)C(=O)N1CCN(Cc2cccc(Cl)c2)CC1

Ordered Check Availability on Manifold View

Design Rationale:

Fragment linking Reaching water/DMSO pocket with a H-Bond acceptor Partly by eye, partly by SeeSAR Michael acceptor as cysteine reactive group

Inspired By:

O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

MED-COV-4280ac29-15

Discussion:

Contributor: Sean McKenna, Trinity College Dublin - Thu, 02 Apr 2020 09:23:59 +0000