Submission Details

KAT-FAI-9b65c29e
Molecule(s):
Cc1cccc(C2CN(C(=O)CS)CCN2c2ccccc2C#N)c1

KAT-FAI-9b65c29e-1

Cc1cccc(C2CN(C(=O)CS)CCN2c2ccccc2C#N)c1

Cc1cccc(C2CN(C(=O)CS)CCN2c2ccccc2N2CCOCC2)c1

KAT-FAI-9b65c29e-2

Cc1cccc(C2CN(C(=O)CS)CCN2c2ccccc2N2CCOCC2)c1

CC1CCCC(C2CN(C(=O)CS)CCN2C2CCCCC2N2CCOCC2)C1

KAT-FAI-9b65c29e-3

CC1CCCC(C2CN(C(=O)CS)CCN2C2CCCCC2N2CCOCC2)C1

Design Rationale:

Covalent inhibitor was optimized for physiochemical/ADME properties.

Inspired By:
Discussion:

Contributor: Kathleen Frey, Fairleigh Dickinson University - Fri, 03 Apr 2020 01:58:55 +0000