Submission Details

ANN-UNI-98d2bf15
Molecule(s):
Cc1ccncc1NC(=O)Cc1ccccc1N

ANN-UNI-98d2bf15-1

Cc1ccncc1NC(=O)Cc1ccccc1N

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1ccncc1NC(=O)Cc1cccc(C(N)=O)c1

ANN-UNI-98d2bf15-2

Cc1ccncc1NC(=O)Cc1cccc(C(N)=O)c1

3-aminopyridine-like Made Check Availability on Manifold View
NC(=O)c1ccncc1NC(=O)Cc1cccc(Cl)c1

ANN-UNI-98d2bf15-3

NC(=O)c1ccncc1NC(=O)Cc1cccc(Cl)c1

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1ccncc1NC(=O)Cc1cccc(OC(F)(F)F)c1

ANN-UNI-98d2bf15-5

Cc1ccncc1NC(=O)Cc1cccc(OC(F)(F)F)c1

3-aminopyridine-like Made Check Availability on Manifold View
Design Rationale:

Compounds building upon ANN-UNI-26382800-5 and TRY-UNI-714a760b-6. Compounds were lipophilic interactions (OCF3) and electrostatic interactions could be picked up were designed by docking.

Discussion:

Contributor: Anna Cederbalk, University of Oxford, ODDI - Wed, 20 May 2020 15:51:29 +0000