Submission Details

MIC-UNK-9582b2c5
Molecule(s):
CC(=O)N1CCC2C(C1)CN(c1cncc3ccccc13)C(=O)C2c1cccc(Cl)c1

MIC-UNK-9582b2c5-1

CC(=O)N1CCC2C(C1)CN(c1cncc3ccccc13)C(=O)C2c1cccc(Cl)c1

3-aminopyridine-like Check Availability on Manifold View
CC(=O)N1CCC2C(CC(c3cncc4ccccc34)C(=O)N2c2cccc(Cl)c2)C1

MIC-UNK-9582b2c5-2

CC(=O)N1CCC2C(CC(c3cncc4ccccc34)C(=O)N2c2cccc(Cl)c2)C1

3-aminopyridine-like Check Availability on Manifold View
CC(=O)N1CCC2C(C1)CN(c1cncc3ccccc13)C(=O)N2c1cccc(Cl)c1

MIC-UNK-9582b2c5-3

CC(=O)N1CCC2C(C1)CN(c1cncc3ccccc13)C(=O)N2c1cccc(Cl)c1

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

It's three-way merger of BEN-DND-93268d01-8, ADA-UCB-6c2cb422-1, and PET-UNK-c9c1e0d8-3. Not sure if N-acetylpiperidine would be at right angle

Other Notes:

It should be possible to make all of these using N-acetylpiperidone and Mannich reaction, Wittig reaction and reductive amination

Inspired By:
Discussion:

Contributor: Michal K - Thu, 27 Aug 2020 08:00:52 +0000