Submission Details
Molecule(s):
CNC(=O)C(CCN1CC2CC1CN2C(=O)CCl)Nc1ccccc1
COc1cc(NC(=O)C2CC3CC2CN3C(=O)CCl)cc(OC)c1OC
CS(=O)(=O)NCC(c1ccccc1)N1CC2CC1CN2C(=O)CCl
N#Cc1ccc(/C=C/C2=CC(N3CC4CC3CN4C(=O)CCl)OC2=O)cc1
NCC1CCc2nc(C3CC4CC3N(C(=O)CCl)C4)sc2C1
NS(=O)(=O)c1ccc2c(c1)CN(CC1CC3CC1CN3C(=O)CCl)CC2
O=C(C(F)Cl)N1CC2CC1CN2Cc1cccc2ccccc12
CC(=O)c1cccc(NC(=O)C2CC3CC2CN3C(=O)CCl)c1
Cc1cccnc1NC(=O)C1CC2CC1CN2C(=O)CCl
COc1ccc(NC(=O)C2CC3CC2CN3C(=O)CCl)cn1
Design Rationale:
ordered chloroacetamides modified by adding an extra C atom above a piperidine or piperazine ring (similar to x0770 transformed into x3077)