Submission Details
Molecule(s):
CCN(Cc1cccc(-c2ccncc2)c1)C(=O)Cn1nnc2ccccc21
CCN(Cc1cccc(-c2ccncc2)c1)C(=O)Cc1noc2ccccc12
O=C(NCc1noc2ccccc12)N(Cc1cccs1)c1ccc(F)cc1
CCOCC(=O)NCc1ccc(CNC(=O)Cn2nnc3ccccc32)cc1
COc1ccccc1C(CNC(=O)Cn1nnc2ccccc21)NC(=O)CNc1nccs1
COc1cc(OC)cc(Oc2ccc(CNC(=O)Cn3nnc4ccccc43)cc2)c1
CN(C(=O)Cn1nnc2ccccc21)c1ccc(Oc2ccc(C(F)(F)F)cn2)cc1
CN(Cc1ccc(OCc2cccs2)cc1)C(=O)Cn1nnc2ccccc21
CN(C(=O)Cc1noc2ccccc12)c1ccc(NC(=O)OC(C)(C)C)cc1
O=C(Cn1nnc2ccccc21)NCc1ccc(Oc2cccnc2)c(F)c1
CN(Cc1nnc2ccccn12)C(=O)N(Cc1cccs1)c1ccc(Br)cc1
Design Rationale:
Prior SARS inhibitors that are present in Enamine Real Space. See here: https://discuss.postera.ai/t/a-brief-exploration-of-past-sars-small-molecule-inhibitors/895/22?u=aaron.morris
Other Notes:
IDs for Enamine in order of submission: s_22____5732348____13206668, s_22____5732348____132823, s_272164____9388766____17338746, m_275592____14114838____15844248____13186276, m_275592____14114668____15844248____15856954, s_22____10119430____13206668, s_22____4934418____13206668, s_22____2263492____13206668, s_22____12335866____132823, s_22____1723102____13206668, s_272164____9388692____9374292,