Submission Details

MIC-UNK-89b52b17
Molecule(s):
O=C(Nc1cncc2ccccc12)[C@]12OCC[C@H]1COc1ccc(Cl)cc12

MIC-UNK-89b52b17-1

O=C(Nc1cncc2ccccc12)[C@]12OCC[C@H]1COc1ccc(Cl)cc12

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)[C@]12OCO[C@H]1COc1ccc(Cl)cc12

MIC-UNK-89b52b17-2

O=C(Nc1cncc2ccccc12)[C@]12OCO[C@H]1COc1ccc(Cl)cc12

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)[C@]12COC[C@H]1COc1ccc(Cl)cc12

MIC-UNK-89b52b17-3

O=C(Nc1cncc2ccccc12)[C@]12COC[C@H]1COc1ccc(Cl)cc12

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)[C@H]1c2cc(Cl)ccc2CN2[C@@H]1CCCS2(=O)=O

MIC-UNK-89b52b17-4

O=C(Nc1cncc2ccccc12)[C@H]1c2cc(Cl)ccc2CN2[C@@H]1CCCS2(=O)=O

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)[C@H]1c2cc(Cl)ccc2CN2[C@@H]1CCS2(=O)=O

MIC-UNK-89b52b17-5

O=C(Nc1cncc2ccccc12)[C@H]1c2cc(Cl)ccc2CN2[C@@H]1CCS2(=O)=O

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Same idea as in EDJ-MED-e4b030d8-11, while making whole thing stiffer Compound 2 could be made (perhaps) from MAT-POS-0c8fa4a7-1, compound 3, maybe, via 3+2 cycloaddition

Inspired By:
Discussion:

Contributor: Michal K - Mon, 03 May 2021 21:07:55 +0000