Submission Details

Molecule(s):
N#CCC1CCN(C(=O)C(=O)N2CN(C(=O)CCl)c3ccccc32)CC1

SAD-SAT-89668ff1-1

N#CCC1CCN(C(=O)C(=O)N2CN(C(=O)CCl)c3ccccc32)CC1

3-aminopyridine-like Check Availability on Manifold View
NS(=O)(=O)c1cccc(C(=O)N2CCC(CNC(=O)CCl)CC2)c1

SAD-SAT-89668ff1-2

NS(=O)(=O)c1cccc(C(=O)N2CCC(CNC(=O)CCl)CC2)c1

C[C@@H](C(=O)Nc1cnccc1C#N)C1CCN(C(=O)CCl)CC1

SAD-SAT-89668ff1-3

C[C@@H](C(=O)Nc1cnccc1C#N)C1CCN(C(=O)CCl)CC1

3-aminopyridine-like Check Availability on Manifold View
N#CC1CC(Nc2ccc(S(N)(=O)=O)cc2)CN(C(=O)CCl)C1

SAD-SAT-89668ff1-4

N#CC1CC(Nc2ccc(S(N)(=O)=O)cc2)CN(C(=O)CCl)C1

N#Cc1ccncc1-c1ccc(S(N)(=O)=O)c(C(N)=O)c1

SAD-SAT-89668ff1-5

N#Cc1ccncc1-c1ccc(S(N)(=O)=O)c(C(N)=O)c1

N#CC1CCCN(C(=O)C(=O)N2CCN(c3ccc(S(N)(=O)=O)cc3)CC2)C1

SAD-SAT-89668ff1-6

N#CC1CCCN(C(=O)C(=O)N2CCN(c3ccc(S(N)(=O)=O)cc3)CC2)C1

N#CC1CCCC(C(=O)C(=O)Nc2cnccc2C(N)=O)C1

SAD-SAT-89668ff1-7

N#CC1CCCC(C(=O)C(=O)Nc2cnccc2C(N)=O)C1

3-aminopyridine-like Check Availability on Manifold View
CC(C#N)C(C(=O)N1CCN(C(=O)CCl)CC1)S(N)(=O)=O

SAD-SAT-89668ff1-8

CC(C#N)C(C(=O)N1CCN(C(=O)CCl)CC1)S(N)(=O)=O

piperazine-chloroacetamide Check Availability on Manifold View
N#Cc1nc(N)ncc1S(=O)(=O)C1CCN(C(=O)CCl)CC1

SAD-SAT-89668ff1-9

N#Cc1nc(N)ncc1S(=O)(=O)C1CCN(C(=O)CCl)CC1

N#CC1=c2ccccc2=CN(C(=O)C(=O)Nc2cc(C(F)(F)F)ccn2)C1

SAD-SAT-89668ff1-10

N#CC1=c2ccccc2=CN(C(=O)C(=O)Nc2cc(C(F)(F)F)ccn2)C1

3-aminopyridine-like Check Availability on Manifold View

Design Rationale:

By eye, designed 10 molecules for class on May 21st

Inspired By:
Discussion: