Submission Details

Molecule(s):
O=C(NCCNc1ccnc2cc(Cl)ccc12)Nc1ccc(F)cc1

GAB-FAC-880f6604-1

O=C(NCCNc1ccnc2cc(Cl)ccc12)Nc1ccc(F)cc1


Design Rationale:

Compound is an analogue of Chloroquine, an antimalarial and immunomodulator drug, which has been tested agains COVID2019 and showed potency in the low micromolar range EC50= 1.13 microMolar. I think it is a good lead

Other Notes:

This and other compounds have been syntheised in my lab using a short 2-step route. Compounds showed antiprotozoal and antitubercular effect, and could shown antiviral properties.

Inspired By:
Discussion: