Submission Details
Molecule(s):
O=C(NCCNc1ccnc2cc(Cl)ccc12)Nc1ccc(F)cc1
Design Rationale:
Compound is an analogue of Chloroquine, an antimalarial and immunomodulator drug, which has been tested agains COVID2019 and showed potency in the low micromolar range EC50= 1.13 microMolar. I think it is a good lead
Other Notes:
This and other compounds have been syntheised in my lab using a short 2-step route. Compounds showed antiprotozoal and antitubercular effect, and could shown antiviral properties.