Submission Details

DAR-DIA-842b4336
Molecule(s):
O=C(Nc1cccnc1)Nc1ccsc1

DAR-DIA-842b4336-1

O=C(Nc1cccnc1)Nc1ccsc1

3-aminopyridine-like Check Availability on Manifold View
Cn1cc(NC(=O)Nc2cccnc2)cn1

DAR-DIA-842b4336-2

Cn1cc(NC(=O)Nc2cccnc2)cn1

3-aminopyridine-like Check Availability on Manifold View
Cc1ccc(NC(=O)Nc2cccnc2)s1

DAR-DIA-842b4336-3

Cc1ccc(NC(=O)Nc2cccnc2)s1

3-aminopyridine-like Made Check Availability on Manifold View
O=C(Nc1cccnc1)Nc1ccc(Cl)s1

DAR-DIA-842b4336-4

O=C(Nc1cccnc1)Nc1ccc(Cl)s1

3-aminopyridine-like Made Check Availability on Manifold View
N#Cc1ccc(NC(=O)Nc2cccnc2)s1

DAR-DIA-842b4336-5

N#Cc1ccc(NC(=O)Nc2cccnc2)s1

3-aminopyridine-like Check Availability on Manifold View
N#Cc1coc(NC(=O)Nc2cccnc2)n1

DAR-DIA-842b4336-6

N#Cc1coc(NC(=O)Nc2cccnc2)n1

3-aminopyridine-like Check Availability on Manifold View
Cc1coc(NC(=O)Nc2cccnc2)n1

DAR-DIA-842b4336-7

Cc1coc(NC(=O)Nc2cccnc2)n1

3-aminopyridine-like Made Check Availability on Manifold View
O=C(Nc1cccnc1)Nc1nc(Cl)co1

DAR-DIA-842b4336-8

O=C(Nc1cccnc1)Nc1nc(Cl)co1

3-aminopyridine-like Check Availability on Manifold View
N#Cc1ccc(NC(=O)Nc2cccnc2)o1

DAR-DIA-842b4336-9

N#Cc1ccc(NC(=O)Nc2cccnc2)o1

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1ccsc1)Nc1cccnc1

DAR-DIA-842b4336-10

O=C(Cc1ccsc1)Nc1cccnc1

3-aminopyridine-like Check Availability on Manifold View
Cn1cc(CC(=O)Nc2cccnc2)cn1

DAR-DIA-842b4336-11

Cn1cc(CC(=O)Nc2cccnc2)cn1

3-aminopyridine-like Check Availability on Manifold View
Cc1ccc(CC(=O)Nc2cccnc2)s1

DAR-DIA-842b4336-12

Cc1ccc(CC(=O)Nc2cccnc2)s1

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1ccc(Cl)s1)Nc1cccnc1

DAR-DIA-842b4336-13

O=C(Cc1ccc(Cl)s1)Nc1cccnc1

3-aminopyridine-like Made Check Availability on Manifold View
N#Cc1ccc(CC(=O)Nc2cccnc2)s1

DAR-DIA-842b4336-14

N#Cc1ccc(CC(=O)Nc2cccnc2)s1

3-aminopyridine-like Check Availability on Manifold View
N#Cc1cnc(CC(=O)Nc2cccnc2)o1

DAR-DIA-842b4336-15

N#Cc1cnc(CC(=O)Nc2cccnc2)o1

3-aminopyridine-like Check Availability on Manifold View
Cc1cnc(CC(=O)Nc2cccnc2)o1

DAR-DIA-842b4336-16

Cc1cnc(CC(=O)Nc2cccnc2)o1

3-aminopyridine-like Made Check Availability on Manifold View
O=C(Cc1cc2cccnc2[nH]1)Nc1ccc(Cl)s1

DAR-DIA-842b4336-17

O=C(Cc1cc2cccnc2[nH]1)Nc1ccc(Cl)s1

3-aminopyridine-like Check Availability on Manifold View
Cc1ccc(NC(=O)Cc2cc3cccnc3[nH]2)s1

DAR-DIA-842b4336-18

Cc1ccc(NC(=O)Cc2cc3cccnc3[nH]2)s1

3-aminopyridine-like Made Check Availability on Manifold View
N#Cc1ccc(NC(=O)Cc2cc3cccnc3[nH]2)s1

DAR-DIA-842b4336-19

N#Cc1ccc(NC(=O)Cc2cc3cccnc3[nH]2)s1

3-aminopyridine-like Check Availability on Manifold View
N#Cc1cnc(NC(=O)Cc2cc3cccnc3[nH]2)o1

DAR-DIA-842b4336-20

N#Cc1cnc(NC(=O)Cc2cc3cccnc3[nH]2)o1

3-aminopyridine-like Check Availability on Manifold View
Cc1cnc(NC(=O)Cc2cc3cccnc3[nH]2)o1

DAR-DIA-842b4336-21

Cc1cnc(NC(=O)Cc2cc3cccnc3[nH]2)o1

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cc2cccnc2[nH]1)Nc1ncc(Cl)o1

DAR-DIA-842b4336-22

O=C(Cc1cc2cccnc2[nH]1)Nc1ncc(Cl)o1

3-aminopyridine-like Check Availability on Manifold View
Cn1cc(NC(=O)Cc2cc3cccnc3[nH]2)cn1

DAR-DIA-842b4336-23

Cn1cc(NC(=O)Cc2cc3cccnc3[nH]2)cn1

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cc2cccnc2[nH]1)Nc1ccsc1

DAR-DIA-842b4336-24

O=C(Cc1cc2cccnc2[nH]1)Nc1ccsc1

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Substitution of ring systems of x0434/x0678/x1093 based on other hits

Inspired By:
Discussion:

Contributor: Daren Fearon, Diamond Light Source Ltd - Mon, 16 Mar 2020 18:45:23 +0000