Submission Details

MAK-UNK-83e0a0b4
Molecule(s):
CCCCc1ccc2c(c1)C(C(=O)N(CCNC1CNC1)c1cncc3cc(CN4CCNCC4)ccc13)CCO2

MAK-UNK-83e0a0b4-1

CCCCc1ccc2c(c1)C(C(=O)N(CCNC1CNC1)c1cncc3cc(CN4CCNCC4)ccc13)CCO2

O=C(C1CCOc2ccc(Cl)cc21)N(CCNC1CNC1)c1cncc2cc(CN3CCNCC3)ccc12

MAK-UNK-83e0a0b4-2

O=C(C1CCOc2ccc(Cl)cc21)N(CCNC1CNC1)c1cncc2cc(CN3CCNCC3)ccc12

3-aminopyridine-like Check Availability on Manifold View
O=C(C1CCOc2ccc(Cl)cc21)N(CCNC1CNC1)c1cncc2ccccc12

MAK-UNK-83e0a0b4-3

O=C(C1CCOc2ccc(Cl)cc21)N(CCNC1CNC1)c1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
CCCCc1ccc2c(c1)C(C(=O)N(CCNC1CNC1)c1cncc3ccccc13)CCO2

MAK-UNK-83e0a0b4-4

CCCCc1ccc2c(c1)C(C(=O)N(CCNC1CNC1)c1cncc3ccccc13)CCO2

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

SeeSAR 9.2 Inspirator, estimated affinity is in nM/pM range

Inspired By:
Discussion:

Contributor: Maksym Voznyy - Sun, 25 Oct 2020 07:11:12 +0000