Submission Details
Molecule(s):
O=C(NC1CCN(C(=O)CCl)CC1NCc1ccccc1)c1ccccc1
Cc1cc(CN(C)C(=O)N2CCC(NC(=O)c3ccccc3)CC2)no1
Design Rationale:
Growing fragment x1351 to try and pick up either interactions with the hydrophobic pocket filled by fragment x0692 or the H bond to His164 that is captured by x0397.