Submission Details
Molecule(s):
CCNc1ccc(Cl)cc1CN1CCN(C(C)=O)CC1
CCNc1ccc(C#N)cc1CN1CCN(C(C)=O)CC1
CC(=O)Nc1ccc(Cl)cc1CN1CCN(C(C)=O)CC1
CC(=O)N1CCN(C2CCNc3ccc(Cl)cc32)CC1
Design Rationale:
Merging fragment X0770 and X0305 by eye. Cyclization of the merged product by eye.
Other Notes:
Synthesis should be fairly straightforward (piperazine alkylations). For the cyclized analogue a reductive amination of the dihydroquinolinone could be performed.